Epidermoid Cysts typically have long T1 (Hypo) and T2 (Hyper) relaxation times and have no enhancement on postcontrast MR images.
EC can show hyperintensity on T1 and T2 MR images, caused by a semiliquid cystic content with high protein concentration. It also can have high signal intensity on T1 and low signal intensity on T2 caused by a combination of high protein content and high viscosity.
EC can show low signal intensity on both T1- and T2-weighted images, with an usual composition of epithelial debris, crystals of cholesterol, and keratin